Safinamide Impurity 46 CAS 2268802-59-9
| CAS No. | 2268802-59-9 |
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Safinamide Impurity 46 (CAS 2268802-59-9, C17H17FN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Safinamide Impurity 46 (C17H17FN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 316.33 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Safinamide Standards
- Safinamide Impurity 4 (CAS CATO-C4X-15904)
- Safinamide Impurity 34 (CAS CATO-C4X-159034)
- Safinamide Impurity 38 (CAS 1827614-91-4)
- Safinamide Impurity 3 (CAS CATO-C4X-15903)
- Safinamide Impurity 2 (CAS 1160513-60-9)
- Safinamide Impurity N1 (CAS 861398-52-9)
- Safinamide (CAS 133865-89-1)
- Safinamide Impurity 31 (CAS 202825-43-2)
Recommended Standards
- Bimatoprost Impurity 25 (CAS 146964-27-4)
- di-tert-butyl (4-(hydroxymethyl)phenyl) phosphate (CAS 857896-79-8)
- Lemborexant impurity 5 (CAS 2541020-22-6)
- (+)-B-Methoxydiisopinocampheylborane (+)-Diisopinocampheylmethoxyborane 99438-28-5 (CAS 99438-28-5)
- Miconazole EP Impurity E CI (CAS CATO-C4X-180232)
- Esomeprazole Impurity 108 (CAS 74409-42-0)
- Fudosteine Impurity 58 HCl (CAS CATO-C4X-144758)
- Tert-butyl (2-(5-formylthiophen-2-yl)phenyl)carbamate (CAS 886509-43-9)
- Phenthoate (CAS 2597-03-7)
- N-(5-methylisoxazol-3-yl)-4-thioureidobenzenesulfonamide (CAS 331422-75-4)
- 3-(iodomethyl)-1λ⁶-thietane-1,1-dione (CAS 1784319-34-1)
- Methyl 4-(benzyloxy)-2-naphthoate (CAS 1823234-09-8)
- C22 Ceramide (CAS 869501-30-4)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
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