Ciprofloxacin EP Impurity F CAS 226903-07-7
| CAS No. | 226903-07-7 |
| Molecular Formula | C17H19N3O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ciprofloxacin EP Impurity F.
CATO supplies Ciprofloxacin EP Impurity F (CAS 226903-07-7), a pharmacopoeial impurity reference standard (molecular formula C17H19N3O4HCl, MW 365.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ciprofloxacin EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 365.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ciprofloxacin EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O4 HCl |
| Molecular Weight | 365.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ciprofloxacin Standards
- Ciprofloxacin EP Impurity C (CAS 103222-12-4)
- Ciprofloxacin Impurity 14 (CAS 103237-52-1)
- Ciprofloxacin-acyl-Beta-D-glucuronide (CAS 105029-31-0)
- Ciprofloxacin impurity 43 (CAS 105093-21-8)
- Ciprofloxacin EP Impurity E (CAS 105394-83-0)
- Ciprofloxacin EP Impurity E（HCl） (CAS 105394-83-0(Free Base))
- Ciprofloxacin Ethyl Ester (CAS 105404-65-7)
- Ciprofloxacin Impurity 15 (CAS 105589-00-2)
Recommended Standards
- Clomifene Impurity 9 (CAS 113454-71-0)
- Nicergoline Impurity 26 (CAS CATO-C4X-208526)
- Nicardipine impurity 22 (CAS CATO-C4X-171022)
- 1-(3-(Bromomethyl)-1H-indazol-1-yl)ethanone (CAS 108185-32-6)
- 4-(5-(4-Bromophenyl)oxazol-2-yl)aniline (CAS 89752-95-4)
- 2-[(4-Chlorophenyl)methanesulfonyl]-1-(2,6-dimethylmorpholin-4-yl)ethan-1-one (CAS 303152-66-1)
- 2-Oxo-1-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxylic acid (CAS 338754-66-8)
- tert-Butyl (4-amino-2-hydroxybutyl)carbamate (CAS 206268-17-9)
- 1-(2-Methyl-5-nitrofuran-3-yl)ethanone (CAS 213469-81-9)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
Why CATO?
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