(Z)-2-(4-chloro-5-oxofuran-2(5H)-ylidene)acetic acid CAS 22752-93-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-2-(4-chloro-5-oxofuran-2(5H)-ylidene)acetic acid.

CATO supplies (Z)-2-(4-chloro-5-oxofuran-2(5H)-ylidene)acetic acid (CAS 22752-93-8), a certified reference material (molecular formula C6H3ClO4, MW 174.54 g/mol) for analytical method development and quality control.

The molecular framework of (Z)-2-(4-chloro-5-oxofuran-2(5H)-ylidene)acetic acid (C6H3ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (Z)-2-(4-chloro-5-oxofuran-2(5H)-ylidene)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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