4-Chloro-6-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine CAS 1027619-77-7
| CAS No. | 1027619-77-7 |
| Molecular Formula | C18H18Cl2N6 |
| Molecular Weight | 389.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-Chloro-6-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 4-Chloro-6-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine (CAS 1027619-77-7), a certified reference material (molecular formula C18H18Cl2N6, MW 389.28 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 4-Chloro-6-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 389.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18Cl2N6 |
| Molecular Weight | 389.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Chloro Standards
- (4-Chloro-5-methyl-pyrimidin-2-yl)-piperidin-2-ylmethyl-amine hydrochloride (CAS 1289384-94-6)
- N-(2-Chloro-6-fluorobenzyl)piperidin-3-amine hydrochloride (CAS 1289385-83-6)
- 4-Chloro-2-[(4-chlorophenyl)methyl]-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine (CAS 867329-94-0)
- 2-Chloro-4-[(2-chlorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338405-97-3)
- 2-Chloro-4-[(3-chlorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338405-96-2)
- 2-Chloro-4-[(4-chlorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338405-95-1)
- 4-Chloro-2-[(2-chlorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338406-03-4)
- 5-Chloro-2-((4-chlorophenyl)carbamoyl)phenyl dimethylsulfamate (CAS 400080-36-6)
Recommended Standards
- 5,7-Dichloro-N-methyl-N-(o-tolyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000576-49-7)
- 4-(4-(Bis(2-chloroethyl)amino)benzylidene)-2-phenyloxazol-5(4H)-one (CAS 18776-75-5)
- 5,7-Dichloro-N-ethyl-N-phenylthiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-46-5)
- 19744-66-2 6-{[(e)-{4-[bis(2-chloroethyl)amino]phenyl}methylidene]amino}-2h-chromen-2-one AR-1H0707 (CAS 19744-66-2)
- 2-(4-(Bis(2-iodoethyl)amino)benzylidene)malononitrile (CAS 92199-03-6)
- 5-Fluoro-2-methylbenzaldehyde (CAS 22062-53-9)
- tert-Butyl (2-(4-iodophenyl)propan-2-yl)carbamate (CAS 850144-83-1)
- methyl (1R,2S,5S)-3-((S)-2-amino-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate (CAS 847737-84-2)
- 1-Bromo-2,4-difluoro-3-methoxybenzene (CAS 221221-00-7)
- 3-Furanmethanol (CAS 4412-91-3)
- 5-Morpholino-2-nitroaniline, >97% (CAS 54998-00-4)
- Ths-044 (CAS 62054-67-5)
- 5-Iodo-4-(1-isopropylpiperidin-4-yl)-N,N-dimethylpyrimidin-2-amine (CAS 1361115-12-9)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com