5-Chloro-3-(phenylthio)-1H-indole CAS 227803-35-2
| CAS No. | 227803-35-2 |
| Molecular Formula | C14H10ClNS |
| Molecular Weight | 259.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-Chloro-3-(phenylthio)-1H-indole (C14H10ClNS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 259.75 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-Chloro-3-(phenylthio)-1H-indole (CAS 227803-35-2), molecular formula C14H10ClNS and molecular weight 259.75 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-3-(phenylthio)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClNS |
| Molecular Weight | 259.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-[2-(methylsulfanyl)phenyl]benzonitrile (CAS 1237083-91-8)
- 1-Chloro-n-(1,2,3,4-tetrahydronaphthalen-1-yl)methanesulfonamide (CAS 1340105-87-4)
- 2-Chloro-N-isopropyl-N-(2-oxo-2-(thiophen-2-yl)ethyl)acetamide (CAS 1353981-22-2)
- 2-Chloro-4-[4-(methylsulfanyl)phenyl]benzonitrile (CAS 1355248-24-6)
- 5-Chloro-2-(phenylthio)-1H-indole (CAS 227803-36-3)
- 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol (CAS 1261229-47-3)
- 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-4-ol (CAS 1261231-33-7)
- 1-{4-[(2-chloro-1,3-thiazol-5-yl)methyl]piperazin-1-yl}ethan-1-one (CAS 865660-24-8)
Recommended Standards
- tert-Butyl (5-chloro-2-mercaptophenyl)carbamate (CAS 2228366-71-8)
- 4-Phenylpiperidine-1-sulfonyl chloride (CAS 727989-58-4)
- 4-Amino-4-(3-chlorophenyl)tetrahydro-2h-thiopyran 1,1-dioxide (CAS 2157359-09-4)
- 4-(4-Chlorobenzyl)thiomorpholine 1,1-dioxide (CAS 477864-21-4)
- 1-(7-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-2,2,2-trifluoroethan-1-one (CAS 181634-14-0)
- 3-(2-Chloro-6-fluorophenyl)-5-methyl-N-(3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)isoxazole-4-carboxamide (CAS 303998-79-0)
- 1,2-Dichloro-4-(iodomethyl)benzene (CAS 142523-67-9)
- 4-Amino-2-(methylthio)pyrimidine-5-carboxaldehyde (CAS 770-31-0)
- Tert-butyl (3R,4S)-3-(aminomethyl)-4-hydroxypiperidine-1-carboxylate (CAS 1083093-27-9)
- N-Methyl-N-(5-methylfuran-2-yl)cyclopentanecarboxamide (CAS 62187-44-4)
- Clopidogrel Impurity 103 (CAS CATO-C4X-1029103)
- Methyl 6-Methylpiperidine-3-carboxylate Hydrochloride (CAS 1009376-74-2)
- 4-(2-Methoxybenzoyl)-6-(p-tolyl)pyridazin-3(2H)-one (CAS 832712-09-1)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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