2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide CAS 227958-10-3
| CAS No. | 227958-10-3 |
| Molecular Formula | C15H15ClF3N5OS |
| Molecular Weight | 405.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 227958-10-3), molecular formula C15H15ClF3N5OS and molecular weight 405.83 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (C15H15ClF3N5OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H15ClF3N5OS |
| Molecular Weight | 405.83 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-N-(4-methoxyphenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 320417-61-6)
- N-(4-Chlorophenyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 338975-87-4)
- (1E)-1-[6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]-N-[4-(trifluoromethyl)phenyl]methanimine (CAS 338404-63-0)
- (E)-({5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}methylidene)amino 2-methylpropanoate (CAS 321553-21-3)
- 1-(5-(4-Chlorophenyl)-7-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)pyrrolidine-2,5-dione (CAS 489414-69-9)
- 3-(2-Chlorophenyl)-N-[(1E)-1,2-dicyano-2-(2,5-dimethyl-1H-pyrrol-1-yl)eth-1-en-1-yl]-5-methyl-1,2-oxazole-4-carboxamide (CAS 861210-02-8)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2,5-dimethoxyphenyl)acetamide (CAS 337354-51-5)
- Methyl 2-({5-[1-(4-chlorophenyl)-4-oxo-1,4-dihydropyridazin-3-yl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetate (CAS 478077-62-2)
Recommended Standards
- (E)-[3,3-Dimethyl-1-(2-nitrophenoxy)butan-2-ylidene]amino N-(3-chlorophenyl)carbamate (CAS 478048-90-7)
- 2-(7-Chloro-4-oxoquinazolin-3(4H)-yl)-N-(4-phenoxyphenyl)acetamide (CAS 618444-17-0)
- N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide (CAS 1646643-53-9)
- 4-{4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl}-3-nitrobenzoic acid (CAS 1427379-13-2)
- 4-((Ethylamino)methyl)tetrahydro-2H-pyran-4-ol (CAS 1342776-86-6)
- 3-Fluoro-1-phenyl-1H-pyrazol-5-ol (CAS 2396658-67-4)
- 17β-Estradiol-d3 3-β-D-Glucuronide (CAS 1260231-06-8)
- Sodium hexabromorhodate(III) hydrate (CAS 32572-90-0)
- 2-Chloro-5-ethynyl-4-methoxypyridine (CAS 1256789-57-7)
- 1-(3,4-Difluorophenyl)-N-(2-methylphenyl)-4-oxo-1,4-dihydropyridazine-3-carboxamide (CAS 478063-37-5)
- 2-bromo-N-(2,4-difluorophenyl)butanamide (CAS 924969-60-8)
- 1-[3-bromo-4-(4-fluoro-2,6-dimethyl-phenoxy)phenyl]ethanone (CAS 2138863-82-6)
- Quintozine，Phenanthrene-d10，Chrysene-d12 (CAS CATO-MCEM501647-DI)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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