N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide CAS 1646643-53-9
| CAS No. | 1646643-53-9 |
| Molecular Formula | C22H16ClN3O3 |
| Molecular Weight | 405.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide (CAS 1646643-53-9) is a high-purity analytical reference standard with the molecular formula C22H16ClN3O3 and a molecular weight of 405.83 g/mol.
The molecular framework of N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide (C22H16ClN3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H16ClN3O3 |
| Molecular Weight | 405.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 4-{4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl}-3-nitrobenzoic acid (CAS 1427379-13-2)
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- tert-Butyl (3-(4-chloro-2-(2,6-difluorobenzoyl)phenyl)prop-2-yn-1-yl)carbamate (CAS 869366-03-0)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 227958-10-3)
- Methyl 4-iodo-2,6-dimethylbenzoate (CAS 200627-65-2)
- 5-(8-Ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole (CAS 2014348-91-3)
- 1-(aminomethyl)-3-(trifluoromethyl)cyclohexan-1-ol hydrochloride (CAS 1803590-25-1)
- 3-Hydroxy-2,2,4-trimethylvaleric Acid Ethyl Ester (CAS 7403-65-8)
- 1,3,5-Triphenyl-1H-pyrazole (CAS 2183-27-9)
- 6-((2-((4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile monohydrochloride (CAS 1797989-42-4)
- 6-Chloro-5-iodo-1H-indazole (CAS 1227269-39-7)
- Emtricitabine Enantiomer S-oxide(S-Isomer) (CAS CATO-C4X-123232)
- 4-(Pyridin-2-yl)piperidin-4-ol hydrochloride (CAS 1346014-80-9)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
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