4-(((tert-Butyldiphenylsilyl)oxy)methyl)-2-chloropyrimidine CAS 2280988-73-8

Purity 97%+In StockPharmaceutical Standards
CAS No.2280988-73-8
Molecular FormulaC21H23ClN2OSi
Molecular Weight382.96 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(((tert-Butyldiphenylsilyl)oxy)methyl)-2-chloropyrimidine CAS 2280988-73-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 4-(((tert-Butyldiphenylsilyl)oxy)methyl)-2-chloropyrimidine (CAS 2280988-73-8), a certified reference material (molecular formula C21H23ClN2OSi, MW 382.96 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 4-(((tert-Butyldiphenylsilyl)oxy)methyl)-2-chloropyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 382.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H23ClN2OSi
Molecular Weight382.96 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentCl-containing
Nitrogen Atoms2

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