Hydroxyzine Impurity 2 CAS CATO-C4X-16602
| CAS No. | CATO-C4X-16602 |
| Molecular Formula | - |
| Molecular Weight | 382.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Hydroxyzine Impurity 2 (CAS CATO-C4X-16602), a pharmacopoeial impurity reference standard (molecular formula C21H19D8ClN2O2, MW 382.95 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Hydroxyzine Impurity 2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 382.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Hydroxyzine Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19D8ClN2O2 |
| Molecular Weight | 382.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Hydroxyzine Standards
- Hydroxyzine-d8DISCONTINUED (CAS 1189480-47-4)
- Hydroxyzine Impurity 5 (CAS 2469273-48-9)
- Hydroxyzine (CAS 68-88-2)
- Hydroxyzine Impurity B Hydrochloride salt (CAS 1263283-80-2)
- Hydroxyzine Impurity 4 (CAS CATO-C4X-16604)
- Hydroxyzine Impurity 1 (CAS 628-89-7)
- Hydroxyzine Pamoate (CAS 10246-75-0)
- Hydroxyzine Impurity 9 (CAS 1031-92-1)
Recommended Standards
- 6,7-Dibromo-8-nitro-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylic acid (CAS 66411-18-5)
- 1,3,2-Dioxaborolane, 2,2′-(2,5-selenophenediyl)bis[4,4,5,5-tetramethyl- (CAS 1611991-43-5)
- 4-(((tert-Butyldiphenylsilyl)oxy)methyl)-2-chloropyrimidine (CAS 2280988-73-8)
- 5-chloro-N-[2-[2,3-dimethyl-4-[2-(1,1,2,2,2-pentadeuterioethoxy)ethyl]phenoxy]ethyl]-6-ethylpyrimidin-4-amine (CAS 1794979-20-6)
- Momelotinib impurity 10 (CAS CATO-C4X-337710)
- Olaparib impurity 154 (CAS CATO-C4X-1135154)
- Sivelestat sodium impurity 46 (CAS CATO-C4X-212346)
- Isocitric Acid Trisodium Salt (Mixture of Diastereomers) (CAS 320-77-4)
- 2-Amino-N-cyclopropylacetamide hydrochloride (CAS 670253-51-7)
- 2-Nitrophenyl trifluoromethanesulphonate (CAS 132993-22-7)
- (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 307952-91-6)
- Atomoxetine Impurity 19 (CAS CATO-C4X-155019)
- Erdosteine (CAS 84611-23-4)
- Peptide 431 (CAS CATO-CPTD788431)
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