1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-oxo-1,2-dihydropyridin-4-yl)oxy)phenyl)urea CAS 228400-57-5
| CAS No. | 228400-57-5 |
| Molecular Formula | C19H13ClF3N3O3 |
| Molecular Weight | 423.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-oxo-1,2-dihydropyridin-4-yl)oxy)phenyl)urea.
CATO supplies 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-oxo-1,2-dihydropyridin-4-yl)oxy)phenyl)urea (CAS 228400-57-5), a certified reference material (molecular formula C19H13ClF3N3O3, MW 423.77 g/mol) for analytical method development and quality control.
Structurally, 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-oxo-1,2-dihydropyridin-4-yl)oxy)phenyl)urea (C19H13ClF3N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 423.77 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H13ClF3N3O3 |
| Molecular Weight | 423.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Ethyl 2-[(1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-ylidene}-2,2,2-trifluoroethyl)sulfanyl]acetate (CAS 1823194-76-8)
- 3-Chloro-N-[(E)-2-[4-(4-methylphenyl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]-2-nitroethenyl]aniline (CAS 400079-88-1)
- 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(4-fluorophenyl)ethan-1-one (CAS 339020-21-2)
- S-(2-Chloro-1,1,2-Trifluoroethyl)Glutathione (CAS 97058-30-5)
- 3-Chloro-5-(trifluoromethyl)-N-({3-[2-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazol-5-yl}methyl)pyridin-2-amine (CAS 1210714-37-6)
- 4-Chloro-6-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine (CAS 1026764-48-6)
- (2Z)-3-{6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl}-2-[3-(trifluoromethyl)phenyl]prop-2-enenitrile (CAS 478248-60-1)
- 3-Benzyl-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-4-hydroxy-1,2-dihydropyridin-2-one (CAS 478247-74-4)
Recommended Standards
- Oxychlordane Isomer (CAS 27304-13-8)
- Ethyl 5-(4-chlorophenoxy)-3-(3-(trifluoromethyl)phenyl)-1,2,4-triazine-6-carboxylate (CAS 338957-79-2)
- 1,3,5-Trioctyl-1,3,5-triazinane (CAS 94279-01-3)
- 2-((4-Chlorobenzyl)thio)-1,1-bis(4-chlorophenyl)ethanol (CAS 252026-68-9)
- 1,1,1,2,2-Pentafluoro-4-iodobutane (CAS 40723-80-6)
- 2,6-Dimethylphenylisocyanate (CAS 28556-81-2)
- Dimethyl 2,2'-(1,2-phenylene)diacetate (CAS 19109-69-4)
- Rel-(1R,3S)-1,3-diphenylpropane-1,3-diol (CAS 5381-86-2)
- (5-Bromo-2-methylthiophen-3-yl)methanol (CAS 1492327-07-7)
- N-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide (CAS 1214429-43-2)
- 6-Chloro-2,3-dimethylbenzoic acid (CAS 5613-24-1)
- Varenicline Impurity 57 (CAS CATO-C4X-196257)
- ethyl 6-chloro-2-methylpyridine-3-carboxylate (CAS 31163-12-9)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
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