2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(4-fluorophenyl)ethan-1-one CAS 339020-21-2
| CAS No. | 339020-21-2 |
| Molecular Formula | C21H14ClF4NO2 |
| Molecular Weight | 423.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(4-fluorophenyl)ethan-1-one.
CATO supplies 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(4-fluorophenyl)ethan-1-one (CAS 339020-21-2), a certified reference material (molecular formula C21H14ClF4NO2, MW 423.79 g/mol) for analytical method development and quality control.
2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(4-fluorophenyl)ethan-1-one (C21H14ClF4NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H14ClF4NO2 |
| Molecular Weight | 423.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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