7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid CAS 228728-13-0

Purity 97%+In StockPharmaceutical Standards
CAS No.228728-13-0
Molecular FormulaC10H10INO2
Molecular Weight303.10 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid CAS 228728-13-0 chemical structure

Description

The occurrence of 7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 228728-13-0) is a high-purity analytical reference standard with the molecular formula C10H10INO2 and a molecular weight of 303.10 g/mol.

Structurally, 7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (C10H10INO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 303.10 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Iodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10INO2
Molecular Weight303.10 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2022
Halogen ContentI-containing
Nitrogen Atoms1

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