tert-Butyl (5-bromo-2-fluoro-3-(trifluoromethyl)phenyl)carbamate CAS 2287287-41-4
| CAS No. | 2287287-41-4 |
| Molecular Formula | C12H12BrF4NO2 |
| Molecular Weight | 358.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies tert-Butyl (5-bromo-2-fluoro-3-(trifluoromethyl)phenyl)carbamate (CAS 2287287-41-4), a certified reference material (molecular formula C12H12BrF4NO2, MW 358.13 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl (5-bromo-2-fluoro-3-(trifluoromethyl)phenyl)carbamate (C12H12BrF4NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl (5-bromo-2-fluoro-3-(trifluoromethyl)phenyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12BrF4NO2 |
| Molecular Weight | 358.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (3-bromo-6-fluoro-2-(trifluoromethyl)phenyl)carbamate (CAS 2126162-32-9)
- 4-Bromo-5-((2,4-difluorophenyl)amino)-2-(2-oxopropyl)pyridazin-3(2H)-one (CAS 477860-36-9)
- Methyl 5-((4-iodophenoxy)methyl)furan-2-carboxylate (CAS 406470-67-5)
- (R)-2-Amino-3-[1-(5-fluoro-2-iodophenyl)ethoxy]pyridine (CAS 1454847-98-3)
- 2,5-Di-tert-butylbenzoic acid (CAS 14034-95-8)
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- tert-butyl N-(6-bromopyrazin-2-yl)-N-tert-butoxycarbonyl-carbamate (CAS 1650548-43-8)
- 1-Methylisoquinoline-5-carbaldehyde (CAS 1369803-36-0)
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Why CATO?
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