1-(3-Aminophenyl)phospholane 1-oxide CAS 2287332-17-4

Description

The occurrence of 1-(3-Aminophenyl)phospholane 1-oxide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-(3-Aminophenyl)phospholane 1-oxide (CAS 2287332-17-4), a certified reference material (molecular formula C10H14NOP, MW 195.20 g/mol) for analytical method development and quality control.

The molecular framework of 1-(3-Aminophenyl)phospholane 1-oxide (C10H14NOP) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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