Anastrozole Impurity 19 CAS 918312-71-7
| CAS No. | 918312-71-7 |
| Molecular Formula | C26H29N3 |
| Molecular Weight | 383.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Anastrozole Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Anastrozole Impurity 19 (CAS 918312-71-7) is a certified pharmaceutical impurity reference standard with the molecular formula C26H29N3 and a molecular weight of 383.53 g/mol.
Anastrozole Impurity 19 (C26H29N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H29N3 |
| Molecular Weight | 383.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related Anastrozole Standards
- Anastrozole EP Impurity D (CAS 1027160-12-8)
- Anastrozole Impurity 21 (CAS CATO-C4X-123921)
- Anastrozole Impurity N2 (CAS 1186102-55-5)
- Anastrozole Impurity 37 (CAS CATO-C4X-123937)
- Anastrozole Impurity 27 (CAS CATO-C4X-123927)
- Anastrozole Diacid (CAS 1338800-81-9)
- Anastrozole Impurity 15 (CAS 2469244-33-3)
- Anastrozole Impurity 16 (CAS 120512-04-1)
Recommended Standards
- N-Dodecyl-2-(1H-imidazole-2-carbonyl)benzamide (CAS 62366-80-7)
- 2-(Difluoromethyl)-5-iodo-6-methoxypyridine-3-sulfonyl chloride (CAS 1805090-10-1)
- N-(3,4-dimethylphenyl)-2-((5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)acetamide (CAS 332161-97-4)
- 4-(Difluoromethyl)-3-iodo-5-methoxypyridine-2-sulfonyl chloride (CAS 1805090-87-2)
- Dapagliflozin Impurity 51 (CAS CATO-C4X-113851)
- Doxofylline Impurity 43 (CAS CATO-C4X-151343)
- Argatroban Impurity 110 (CAS CATO-C4X-1007110)
- N,N-Dimethyl-3-nitrobenzenesulfonamide (CAS 26199-83-7)
- 5,6-O-Isopropylidene-1,4-bis-O-(phenylmethyl)-DL-myo-Inositol (CAS 173828-64-3)
- Acetaminophen Impurity 44 (CAS 102019-96-5)
- 2-(5-Cyclobutyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride (CAS 1380300-78-6)
- 2-Bromo-1-(bromomethyl)-3-iodobenzene (CAS 1261649-03-9)
- 3-{4-[(E)-2-Chloro-but-2-en-(E)-ylidene]-5-methyl-ene-4,5-dihydro-1H-imidazol-2-yl}-propionic acid (CAS 878431-45-9)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
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