5-Nitro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one CAS 22902-67-6
| CAS No. | 22902-67-6 |
| Molecular Formula | C6H4N4O3 |
| Molecular Weight | 180.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Nitro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one.
5-Nitro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one (CAS 22902-67-6), molecular formula C6H4N4O3 and molecular weight 180.12 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H4N4O3, 5-Nitro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 180.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4N4O3 |
| Molecular Weight | 180.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 4 |
Related Nitro Standards
- 5-Nitro-1h,2h,3h-pyrazolo[3,4-b]pyridin-3-one (CAS 1186609-73-3)
- 7-Nitro-3H-imidazo[4,5-b]pyridine 4-oxide (CAS 14432-11-2)
- 2-Nitro-1H-purin-6-amine (CAS 501950-35-2)
- 5-Nitro-1h-1,2,3-benzotriazol-1-ol (CAS 64352-55-2)
- 5-Nitro-2,3-dihydro-1,3-benzoxazol-2-one (CAS 3889-13-2)
- 5-nitro-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one (CAS 22277-00-5)
- 6-Nitro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 80773-01-9)
- 7-Nitro-1,2-benzisoxazol-3(2H)-one (CAS 60357-78-0)
Recommended Standards
- 4-Oxo-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-3-carboxylic acid (CAS 864872-01-5)
- 4-Nitrobenzoxazole-2(3H)-one (CAS 28955-71-7)
- 4-Methyl-1,4-dihydrobis([1,2,5]oxadiazolo)[3,4-b:3',4'-e]pyrazine (CAS 212391-77-0)
- 4-azido-3-nitrophenol (CAS 6086-33-5)
- 2-(4-Chlorophenyl)-1-((3-(trifluoromethyl)benzyl)oxy)-1H-imidazo[4,5-b]pyridine (CAS 339009-91-5)
- 3-Chloro-2-({5-[(1E)-1-[(E)-2-[1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)ethylidene]hydrazin-1-ylidene]ethyl]thiophen-2-yl}methyl)-5-(trifluoromethyl)pyridine (CAS 321432-69-3)
- (1S,3S)-3-((tert-Butoxycarbonyl)amino)cyclopentanecarboxylic acid (CAS 161601-29-2)
- (1R,2R)-2-(2,5-dimethylphenyl)cyclopropane-1-carboxylic acid (CAS 2227661-18-7)
- 2-(7-Bromo-2-oxo-2,3-dihydro-1h-indol-3-yl)acetic acid (CAS 1368516-03-3)
- 3-Isopropyl-1H-pyrazole-4-carbaldehyde (CAS 154926-99-5)
- 4-(Decanoyloxy)benzoic acid (CAS 86960-46-5)
- Ethyl 2-(4-chloro-1h-pyrazol-1-yl)propanoate (CAS 51292-38-7)
- n-Methoxy-n,5-dimethylthiophene-2-carboxamide (CAS 132960-12-4)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com