7-Nitro-1,2-benzisoxazol-3(2H)-one CAS 60357-78-0
| CAS No. | 60357-78-0 |
| Molecular Formula | C7H4N2O4 |
| Molecular Weight | 180.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-Nitro-1,2-benzisoxazol-3(2H)-one (CAS 60357-78-0), a certified reference material (molecular formula C7H4N2O4, MW 180.12 g/mol) for analytical method development and quality control.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 7-Nitro-1,2-benzisoxazol-3(2H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 180.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4N2O4 |
| Molecular Weight | 180.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
Related Nitro Standards
- 5-Nitro-1h,2h,3h-pyrazolo[3,4-b]pyridin-3-one (CAS 1186609-73-3)
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- 2-Nitro-1H-purin-6-amine (CAS 501950-35-2)
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Recommended Standards
- 6-Oxo-6,7-dihydro-3H-purine-8-carboxylic acid (CAS 98141-78-7)
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- 6-Nitrobenzoxazole-2(3H)-one (CAS 4694-91-1)
- 7-Nitro-1H-imidazo[4,5-c]pyridin-4(5H)-one (CAS 306272-95-7)
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