5-(5-(Trifluoromethyl)isoxazol-3-yl)thiophene-2-sulfonyl chloride CAS 229956-98-3
| CAS No. | 229956-98-3 |
| Molecular Formula | C8H3ClF3NO3S2 |
| Molecular Weight | 317.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(5-(Trifluoromethyl)isoxazol-3-yl)thiophene-2-sulfonyl chloride (CAS 229956-98-3), molecular formula C8H3ClF3NO3S2 and molecular weight 317.69 g/mol, is a CATO reference standard with documented purity and traceability.
5-(5-(Trifluoromethyl)isoxazol-3-yl)thiophene-2-sulfonyl chloride (C8H3ClF3NO3S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF3NO3S2 |
| Molecular Weight | 317.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Trifluoromethyl Standards
- 4-(5-(Trifluoromethyl)isoxazol-3-yl)thiophene-2-sulfonyl chloride (CAS 1268334-85-5)
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Recommended Standards
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- 4-(4-Chlorophenoxy)-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 338792-32-8)
- Metflurazon (CAS 23576-23-0)
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- 3-(6-Methoxy-2-pyridyl)-2-methyl-1-propene (CAS 951886-80-9)
- 2,5-DIhydroxybenzoic acid butylamine salt (CAS 666174-80-7)
- Methyl 3-{[(2-aminoethyl)sulfanyl]methyl}benzoate (CAS 1094651-21-4)
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- Gliclazide EP Impurity D (CAS 1136426-19-1)
- 1-Bromo-3-butoxy-2-fluorobenzene (CAS 1881289-43-5)
- 8-chloro-3,4-dihydro-2H-1-benzopyran-4-ol (CAS 1176104-70-3)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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