1-(tert-butyl) 2-Methyl (2R,4S)-4-(difluoromethyl)pyrrolidine-1,2-dicarboxylate CAS 2301881-90-1
| CAS No. | 2301881-90-1 |
| Molecular Formula | C12H19F2NO4 |
| Molecular Weight | 279.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 1-(tert-butyl) 2-Methyl (2R,4S)-4-(difluoromethyl)pyrrolidine-1,2-dicarboxylate (CAS 2301881-90-1), a certified reference material (molecular formula C12H19F2NO4, MW 279.28 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(tert-butyl) 2-Methyl (2R,4S)-4-(difluoromethyl)pyrrolidine-1,2-dicarboxylate is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 279.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-(tert-butyl) 2-Methyl (2R,4S)-4-(difluoromethyl)pyrrolidine-1,2-dicarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H19F2NO4 |
| Molecular Weight | 279.28 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 1-(tert-Butyl) 2-methyl (2R,4R)-4-(difluoromethyl)pyrrolidine-1,2-dicarboxylate (CAS 2301881-89-8)
- 1-(Tert-butyl) 3-methyl (R)-5,5-difluoropiperidine-1,3-dicarboxylate (CAS 2198312-55-7)
- 1-(Tert-butoxycarbonyl)-6,6-difluoroazepane-4-carboxylic acid (CAS 2306275-81-8)
- 1-(Tert-butyl) 3-methyl (S)-5,5-difluoropiperidine-1,3-dicarboxylate (CAS 2306248-87-1)
- 1,3-Isobenzofurandione, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol and 2,5-furandione, isononanoate (CAS 79770-81-3)
- 1-Boc-2-[2-(trifluoromethyl)benzyl]hydrazine (CAS 1690617-00-5)
- 4-(4-Fluorophenyl)-1H-pyrrole-2-carboxylic acid (CAS 855672-46-7)
- 3-Bromo-6,7,8,9-tetrahydro-5H-pyrido[3,2-b]indole (CAS 2231675-92-4)
- 4-Nitro-2-(trifluoromethyl)pyridine 1-oxide (CAS 147149-97-1)
- 1-(Cyclopropylmethyl)-2-methyl-1H-imidazole (CAS 1342433-69-5)
- 3-(Ethoxycarbonyl)-1-(4-nitrophenyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264042-47-8)
- (4,4-Dimethyl-cyclohexyl)-acetic acid methyl ester (CAS 1210879-61-0)
- 2-Fluoro-1-[2-(trifluoromethyl)phenyl]ethanamine (CAS 929972-10-1)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
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