(R)-3-Cyanopyrrolidine-1-sulfonyl chloride CAS 2301886-37-1
| CAS No. | 2301886-37-1 |
| Molecular Formula | C5H7ClN2O2S |
| Molecular Weight | 194.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 194.64 g/mol gives (R)-3-Cyanopyrrolidine-1-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(R)-3-Cyanopyrrolidine-1-sulfonyl chloride (CAS 2301886-37-1) is a high-purity analytical reference standard with the molecular formula C5H7ClN2O2S and a molecular weight of 194.64 g/mol.
The molecular framework of (R)-3-Cyanopyrrolidine-1-sulfonyl chloride (C5H7ClN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7ClN2O2S |
| Molecular Weight | 194.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related R Standards
- (S)-3-Cyanopyrrolidine-1-sulfonyl chloride (CAS 2301083-01-0)
- 1-Boc-2-cyanopyrrolidine (CAS 144688-70-0)
- 1-Cbz-2-cyanopyrrolidine (CAS 119020-06-3)
- Benzyl 3-cyanopyrrolidine-1-carboxylate (CAS 188846-99-3)
- Methyl 2-cyanopyrrolidine-1-carboxylate (CAS 130147-41-0)
- Methyl 1-cyanopyrrolidine-2-carboxylate (CAS 367906-67-0)
- Methyl 1-cyanopyrrolidine-3-carboxylate (CAS 367906-55-6)
- Methyl 4-cyanopyrrolidine-3-carboxylate (CAS 344294-42-4)
Recommended Standards
- 2,5-Dimethylfuran-3-sulfonyl chloride (CAS 166964-26-7)
- 5-chloro-6-fluoro-pyrazolo[1,5-a]pyrimidin-7-amine (CAS 1610021-35-6)
- 1,2-Dimethyl-1H-imidazole-5-sulfonyl chloride (CAS 849351-92-4)
- (1-Methyl-1h-imidazol-2-yl)methanesulfonyl chloride (CAS 1420847-32-0)
- 2-(3,6-Di(azetidin-1-yl)xanthylium-9-yl)-4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)benzoate (CAS 1811539-32-8)
- (Z)-[4-(Benzenesulfonyl)butan-2-ylidene][(4-chlorophenyl)methoxy]amine (CAS 306979-46-4)
- rel-2,2-Difluoro-3-methylcyclopropane-1-carboxylic acid (CAS 2247657-28-7)
- Ethyl 4-(benzo[d][1,3]dioxol-5-yl)-4-oxobutanoate (CAS 951889-25-1)
- Lurasidone Impurity 51 (CAS 1318074-22-4)
- 6-bromo-N-methoxy-N-methylchroman-2-carboxamide (CAS 2007917-02-2)
- 1-Cyclopentyl-2-imino-10-methyl-3-tosyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606954-90-9)
- Epinephrine Impurity 87 (CAS CATO-C4X-184987)
- N-((5-(allylthio)-4-isopropyl-4H-1,2,4-triazol-3-yl)methyl)-2-methylbenzamide (CAS 400085-68-9)
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