Varenicline Impurity 65 CAS 2306217-15-0
| CAS No. | 2306217-15-0 |
| Molecular Formula | C17H17N3O5 |
| Molecular Weight | 343.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Varenicline Impurity 65 (C17H17N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Varenicline Impurity 65 (CAS 2306217-15-0), a pharmacopoeial impurity reference standard (molecular formula C17H17N3O5, MW 343.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Varenicline Impurity 65 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17N3O5 |
| Molecular Weight | 343.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 3 |
Related Varenicline Standards
- Varenicline Impurity 63 (CAS CATO-C4X-196263)
- Varenicline Nitroso Impurity 4 (CAS CATO-C1911208)
- Varenicline Metadinitro (CAS 853946-18-6)
- Varenicline Impurity 20 (CAS 230615-59-5)
- Varenicline Impurity 51 (CAS CATO-C4X-196251)
- Varenicline Impurity 50 (CAS CATO-C4X-196250)
- Varenicline Impurity 7 (CAS 357426-10-9)
- Varenicline Impurity 56 (CAS CATO-C4X-196256)
Recommended Standards
- Crisaborole impurity 128 (CAS CATO-C4X-2021128)
- Erlotinib Impurity 70 (CAS CATO-C4X-106970)
- Boc-Gln-OSu (CAS 18800-78-7)
- Erlotinib Impurity 69 (CAS CATO-C4X-106969)
- Dorzagliatin Impurity 7 (CAS CATO-C4X-34417)
- Cefmetazole Impurity 38 (CAS CATO-C4X-150738)
- Varenicline Impurity 5 (CAS 950781-89-2)
- Pterosin A (CAS 35910-16-8)
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- Ethyl (E)-3-(4-Imidazolyl)acrylate (CAS 111157-51-8)
- (1-Isopropyl-1H-imidazol-2-yl)methanamine dihydrochloride (CAS 53332-68-6)
- 4-Bromo-3-methoxypyridine 1-oxide (CAS 109911-37-7)
- n-Allyl-2-(benzo[d]thiazol-2-ylthio)acetamide (CAS 565417-76-7)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com