Varenicline Impurity 63 CAS CATO-C4X-196263
| CAS No. | CATO-C4X-196263 |
| Molecular Formula | C17H17N3O5 |
| Molecular Weight | 343.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Varenicline Impurity 63 (C17H17N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Varenicline Impurity 63 (CAS CATO-C4X-196263) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17N3O5 and a molecular weight of 343.33 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H17N3O5 |
| Molecular Weight | 343.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Varenicline Standards
- Varenicline Impurity 65 (CAS 2306217-15-0)
- Varenicline Nitroso Impurity 4 (CAS CATO-C1911208)
- Varenicline Metadinitro (CAS 853946-18-6)
- Varenicline Impurity 20 (CAS 230615-59-5)
- Varenicline Impurity 51 (CAS CATO-C4X-196251)
- Varenicline Impurity 50 (CAS CATO-C4X-196250)
- Varenicline Impurity 7 (CAS 357426-10-9)
- Varenicline Impurity 56 (CAS CATO-C4X-196256)
Recommended Standards
- Erlotinib Impurity 70 (CAS CATO-C4X-106970)
- Erlotinib Impurity 69 (CAS CATO-C4X-106969)
- Crisaborole impurity 128 (CAS CATO-C4X-2021128)
- Propargyl-PEG3-O-CH2-NHS ester (CAS 2144777-76-2)
- Atomoxetine Impurity 54 (CAS CATO-C4X-155054)
- Mupirocin Calcium EP Impurity I (CAS CATO-C4X-170616)
- Fluocinolone Acetonide Impurity 24 (CAS CATO-C4X-238124)
- 6-(9H-fluoren-2-yl)pyridazin-3-ol (CAS 1105193-90-5)
- 2-(6-Methylimidazo[2,1-b]thiazol-5-yl)-5-(propa-1,2-dien-1-ylthio)-1,3,4-oxadiazole (CAS 400088-41-7)
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclobutanecarbonitrile (CAS 1314772-15-0)
- 4,6-Dioxoheptanoic acid (CAS 51568-18-4)
- 2-Amino-N-(8-hydroxy-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide (CAS 2132943-86-1)
- 4,6-Difluoroisobenzofuran-1(3H)-one (CAS 1288986-24-2)
- Serpent Peptide (CAS 823202-99-9)
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