Tert-butyl (3S,6S)-6-(bromomethyl)-1,1-difluoro-5-azaspiro[2.4]Heptane-5-carboxylate CAS 2306244-81-3
| CAS No. | 2306244-81-3 |
| Molecular Formula | C12H18BrF2NO2 |
| Molecular Weight | 326.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Tert-butyl (3S,6S)-6-(bromomethyl)-1,1-difluoro-5-azaspiro[2.4]Heptane-5-carboxylate (CAS 2306244-81-3) is a high-purity analytical reference standard with the molecular formula C12H18BrF2NO2 and a molecular weight of 326.18 g/mol.
Tert-butyl (3S,6S)-6-(bromomethyl)-1,1-difluoro-5-azaspiro[2.4]Heptane-5-carboxylate (C12H18BrF2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Tert-butyl (3S,6S)-6-(bromomethyl)-1,1-difluoro-5-azaspiro[2.4]Heptane-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18BrF2NO2 |
| Molecular Weight | 326.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (3R,6S)-6-(bromomethyl)-1,1-difluoro-5-azaspiro[2.4]Heptane-5-carboxylate (CAS 2306245-77-0)
- Minodronic Impurity 3 (CAS CATO-C4X-12413)
- 4-Chloro-6-(4-chlorophenyl)-2-phenylpyrimidine-5-carbonitrile (CAS 338976-31-1)
- 2-Bromo-1-(2-phenylquinolin-4-yl)ethanone (CAS 101575-93-3)
- 5,6-Dimethyl-2-(4-(trifluoromethyl)phenyl)pyrimidin-4-ol (CAS 180606-46-6)
- 3-(3-Bromo-5-fluorobenzyl)oxazolidin-2-one (CAS 1513688-85-1)
- 2-Morpholino-3-(2,2,2-trifluoroacetyl)-4H-benzo[h]chromen-4-one (CAS 1951441-99-8)
- 2'-(Benzyloxy)-[1,1'-biphenyl]-2-amine hydrochloride (CAS 1170524-29-4)
- 2-(Chloromethyl)-4-(difluoromethyl)-5-hydroxypyridine-3-methanol (CAS 1805069-26-4)
- (3-(5-Bromofuran-2-yl)phenyl)methanol (CAS 89929-92-0)
- 2-(Cyclopropylmethoxy)nicotinonitrile (CAS 1019493-32-3)
- tert-butyl 1-(aminomethyl)cyclobutane-1-carboxylate (CAS 1366068-12-3)
- 2-(4-(Aminomethyl)-5-(difluoromethyl)-6-iodopyridin-3-yl)acetonitrile (CAS 1805264-01-0)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com