4-Chloro-6-(4-chlorophenyl)-2-phenylpyrimidine-5-carbonitrile CAS 338976-31-1
| CAS No. | 338976-31-1 |
| Molecular Formula | C17H9Cl2N3 |
| Molecular Weight | 326.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6-(4-chlorophenyl)-2-phenylpyrimidine-5-carbonitrile.
4-Chloro-6-(4-chlorophenyl)-2-phenylpyrimidine-5-carbonitrile (CAS 338976-31-1), molecular formula C17H9Cl2N3 and molecular weight 326.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-6-(4-chlorophenyl)-2-phenylpyrimidine-5-carbonitrile (C17H9Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H9Cl2N3 |
| Molecular Weight | 326.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
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- 4-Chloro-3-(difluoromethyl)-5-fluoro-2-methoxypyridine (CAS 1805057-94-6)
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- 1,4-Bis(2-(2,4-dichlorobenzylidene)hydrazinyl)phthalazine (CAS 27702-21-2)
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- 4-Ethyl-5-methyl-1H-pyrrole-2-carboxamide (CAS 125342-47-4)
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