3-Bromo-2-chloro-6H-pyrano[3,4-b]pyridin-5(8H)-one CAS 2306276-90-2
| CAS No. | 2306276-90-2 |
| Molecular Formula | C8H5BrClNO2 |
| Molecular Weight | 262.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Bromo-2-chloro-6H-pyrano[3,4-b]pyridin-5(8H)-one.
3-Bromo-2-chloro-6H-pyrano[3,4-b]pyridin-5(8H)-one (CAS 2306276-90-2), molecular formula C8H5BrClNO2 and molecular weight 262.49 g/mol, is a CATO reference standard with documented purity and traceability.
3-Bromo-2-chloro-6H-pyrano[3,4-b]pyridin-5(8H)-one (C8H5BrClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClNO2 |
| Molecular Weight | 262.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-Bromo-2-chloro-3-methylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one (CAS 2482719-45-7)
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- 1,1,1,3,3-Pentamethyl-3-(3-(oxiran-2-ylmethoxy)propyl)disiloxane (CAS 18044-44-5)
- 7-Bromo-6-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 5791-56-0)
- 2-[(4-Methoxyphenyl)sulfanyl]-5-(trifluoromethyl)benzenecarbonitrile (CAS 212691-83-3)
- Nitromalonaldehyde Sodium Hydrate (CAS 53821-72-0)
- 2-chloro-4-(4-fluorophenoxy)pyrimidine (CAS 1090835-72-5)
- (1-(4-Methylbenzyl)piperidin-3-yl)methanamine hydrochloride (CAS 1303967-55-6)
- des-9-Pro-Cetrorelix (CAS CATO-C4X-201447)
- 5-Bromo-2,3-difluoro-4-(trimethylsilyl)benzoic acid (CAS 1241948-58-2)
- (1R,2S,6S)-Bicyclo[4.1.0]heptan-2-ol (CAS 200883-45-0)
- Isoxazole-4-carboxylic acid methyl ester (CAS 15166-81-1)
- 1-2-3-4-Tetra-O-benzyl-β-D-glucopyranoside (CAS 27851-29-2)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
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