Dexchlorpheniramine EP Impurity B Maleate CAS 23095-76-3
| CAS No. | 23095-76-3 |
| Molecular Formula | C16H19ClN2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dexchlorpheniramine EP Impurity B Maleate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dexchlorpheniramine EP Impurity B Maleate (CAS 23095-76-3) is a certified pharmaceutical impurity reference standard with the molecular formula C16H19ClN2C4H4O4 and a molecular weight of 390.86 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Dexchlorpheniramine EP Impurity B Maleate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 390.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN2 C4H4O4 |
| Molecular Weight | 390.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dexchlorpheniramine Standards
- Dexchlorpheniramine impurity 10 (CAS 19428-44-5)
- Dexchlorpheniramine impurity 12 (CAS 2734416-85-2)
- Dexchlorpheniramine EP Impurity B (CAS 32188-09-3)
- Dexchlorpheniramine impurity 113 (CAS 694490-86-3)
- Dexchlorpheniramine Impurity 8 (CAS 78539-96-5)
- Dexchlorpheniramine Impurity 6 (CAS CATO-C4X-16116)
- Dexchlorpheniramine Impurity 7 (CAS CATO-C4X-16117)
- Dexchlorpheniramine Impurity 8 (CAS CATO-C4X-16118)
Recommended Standards
- Fluticasone Impurity N2 (CAS 397864-41-4)
- Vibegron Impurity 11 (CAS CATO-C4X-237611)
- Iguratimod Impurity 125 (CAS CATO-C4X-1826125)
- 2-Chloro-3-hydroxynaphthalene-1,4-dione (CAS 1526-73-4)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-allylpent-4-enoic acid (CAS 1311992-97-8)
- tert-Butyl (3S,5R)-3,4,5-trimethylpiperazine-1-carboxylate (CAS 1152111-15-3)
- 2-(Cyclopent-1-en-1-yl)acetonitrile (CAS 22734-04-9)
- Methyl 4-O-[4-6-O-benzylidene)-β-D-galactopyranosyl] β-D-glucopyranoside (CAS 56865-31-7)
- Nonan-4-one (CAS 4485-09-0)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com