1-Chloro-4-(chloromethyl)-2-(trifluoromethyl)benzene CAS 23131-73-9
| CAS No. | 23131-73-9 |
| Molecular Formula | C8H5Cl2F3 |
| Molecular Weight | 229.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-4-(chloromethyl)-2-(trifluoromethyl)benzene (CAS 23131-73-9), molecular formula C8H5Cl2F3 and molecular weight 229.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/chlorine substitution, an aromatic ring system, 1-Chloro-4-(chloromethyl)-2-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 229.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Chloro-4-(chloromethyl)-2-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2F3 |
| Molecular Weight | 229.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-Chloro-2-(chloromethyl)-3-(trifluoromethyl)benzene (CAS 1228898-68-7)
- 1-Chloro-3-(chloromethyl)-5-(trifluoromethyl)benzene (CAS 1228898-69-8)
- 1-Chloro-2-(chloromethyl)-4-(trifluoromethyl)benzene (CAS 22902-87-0)
- 2-Chloro-1-(chloromethyl)-3-(trifluoromethyl)benzene (CAS 22902-94-9)
- 2-Chloro-1-(chloromethyl)-4-(trifluoromethyl)benzene (CAS 24096-63-7)
- 2-Chloro-4-(chloromethyl)-1-(trifluoromethyl)-benzene (CAS 75462-56-5)
- 4-Chloro-1-(chloromethyl)-2-(trifluoromethyl)benzene (CAS 24096-64-8)
- 3-Chloro-5-fluorobenzenesulfonyl chloride (CAS 1131397-73-3)
Recommended Standards
- 2-(2-Bromophenyl)-2-oxoacetic acid (CAS 26767-16-8)
- 1,2-Dichloro-4-methyl-5-(trifluoromethyl)benzene (CAS 74483-51-5)
- 2-(3-Bromophenyl)-2-oxoacetic acid (CAS 7194-78-7)
- 1-(Dichloromethyl)-4-(trifluoromethyl)benzene (CAS 82510-98-3)
- (1-Propyl-1h-imidazol-5-yl)methanesulfonyl chloride (CAS 1463418-95-2)
- 4-(3-Bromophenyl)-2,5-dimethylpyrazol-3-amine (CAS 1156165-95-5)
- Ethyl 4-amino-3,5-dimethyl-1H-pyrrole-2-carboxylate (CAS 100818-55-1)
- 1-(Methylamino)-3-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propan-2-ol (CAS 801228-17-1)
- Hydroxytuberosone (CAS 95456-43-2)
- 5'-Bromo-[1,1':3',1''-terphenyl]-4,4''-diamine (CAS 2337335-29-0)
- 5-(4-Fluorobenzyl)-2,3-dihydrobenzo[f][1,2,5]thiadiazepin-4(5H)-one 1,1-dioxide (CAS 1355206-23-3)
- [1-(2-Chloro-acetyl)-pyrrolidin-2-ylmethyl]-cyclopropyl-carbamic acid benzyl ester (CAS 1354015-16-9)
- N-(4,6-dimethylpyridin-2-yl)-3-oxobutanamide (CAS 23600-26-2)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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