1-Chloro-2-(chloromethyl)-3-(trifluoromethyl)benzene CAS 1228898-68-7
| CAS No. | 1228898-68-7 |
| Molecular Formula | C8H5Cl2F3 |
| Molecular Weight | 229.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-Chloro-2-(chloromethyl)-3-(trifluoromethyl)benzene (CAS 1228898-68-7), a certified reference material (molecular formula C8H5Cl2F3, MW 229.03 g/mol) for analytical method development and quality control.
Structurally, 1-Chloro-2-(chloromethyl)-3-(trifluoromethyl)benzene (C8H5Cl2F3) contains fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 229.03 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Chloro-2-(chloromethyl)-3-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2F3 |
| Molecular Weight | 229.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-Chloro-3-(chloromethyl)-5-(trifluoromethyl)benzene (CAS 1228898-69-8)
- 1-Chloro-2-(chloromethyl)-4-(trifluoromethyl)benzene (CAS 22902-87-0)
- 1-Chloro-4-(chloromethyl)-2-(trifluoromethyl)benzene (CAS 23131-73-9)
- 2-Chloro-1-(chloromethyl)-3-(trifluoromethyl)benzene (CAS 22902-94-9)
- 2-Chloro-1-(chloromethyl)-4-(trifluoromethyl)benzene (CAS 24096-63-7)
- 2-Chloro-4-(chloromethyl)-1-(trifluoromethyl)-benzene (CAS 75462-56-5)
- 4-Chloro-1-(chloromethyl)-2-(trifluoromethyl)benzene (CAS 24096-64-8)
- 3-Chloro-5-fluorobenzenesulfonyl chloride (CAS 1131397-73-3)
Recommended Standards
- 7-Bromo-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one (CAS 1228013-76-0)
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- 6-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 1245708-13-7)
- 7-Bromo-2H-pyrido[3,2-β][1,4]oxazin-3(4H)-one (CAS 122450-96-8)
- 2-(5-Bromo-2-fluorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244087-61-2)
- 3-Ethoxy-1-(thiophen-2-yl)prop-2-en-1-one (CAS 143304-05-6)
- 2-Acetamido-3-(2,3-dichlorophenyl)propanoic acid (CAS 1260662-69-8)
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