tert-Butyl (3S,4R)-3-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate CAS 2325666-22-4
| CAS No. | 2325666-22-4 |
| Molecular Formula | C10H17F2NO3 |
| Molecular Weight | 237.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures tert-Butyl (3S,4R)-3-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
tert-Butyl (3S,4R)-3-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate (CAS 2325666-22-4) is a high-purity analytical reference standard with the molecular formula C10H17F2NO3 and a molecular weight of 237.24 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl (3S,4R)-3-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H17F2NO3 |
| Molecular Weight | 237.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (2S,4R)-2-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate (CAS 2810050-73-6)
- Tert-butyl (R)-3,3-difluoro-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 2199215-19-3)
- rel-(3R,4S)-tert-Butyl 3-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate (CAS 2368911-11-7)
- tert-Butyl (R)-4,4-difluoro-3-hydroxypiperidine-1-carboxylate (CAS 2306249-01-2)
- 2-Chloro-1-(4-methyl-decahydroquinolin-1-yl)ethan-1-one (CAS 76395-69-2)
- (4-Aminopiperidin-1-yl)(4-methoxyphenyl)methanone (CAS 886507-49-9)
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- (3,5-Dimethoxy-4-hydroxyphenyl)acetamide (CAS 42973-68-2)
- (5-(Furan-2-yl)pyridin-3-yl)methanamine (CAS 1346687-17-9)
- (2S,5R)-5-(fluoromethyl)-2-methylpiperidine hydrochloride (CAS 2306255-48-9)
- 2-(Pentanoyloxy)benzoic acid (CAS 64206-54-8)
- 6-(4-Methylpiperazin-1-yl)-11H-dibenzo[b,e]azepine (CAS 1977-11-3)
- 4-(2-(4-Fluorophenyl)acetyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 941994-77-0)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com