Methyl 3-Chloro-4-fluorobenzoate CAS 234082-35-0
| CAS No. | 234082-35-0 |
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Methyl 3-Chloro-4-fluorobenzoate (CAS 234082-35-0), a certified reference material (molecular formula C8H6ClFO2, MW 188.58 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 3-Chloro-4-fluorobenzoate (C8H6ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2023 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- Methyl 3-chloro-2-fluorobenzoate (CAS 773874-05-8)
- Methyl 3-chloro-5-fluorobenzoate (CAS 327056-75-7)
- Methyl 2-chloro-5-fluorobenzoate (CAS 647020-63-1)
- Methyl 4-Chloro-3-fluorobenzoate (CAS 206362-87-0)
- (3-Isopropyl-2-phenyloxazolidin-5-yl)methanol (CAS 54126-58-8)
- tert-Butyl ((4-chloro-6-formylpyridin-2-yl)methyl)carbamate (CAS 1393582-10-9)
- Ethyl 2-methyl-6-oxo-1,2-dihydro-6H-pyrrolo-[3,2,1-ij]quinoline-5-carboxylate (CAS 57771-88-7)
- (1-(3-Bromophenyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 944905-68-4)
- 2-[1-Benzyl-3-(tert-butyl)-1H-1,2,4-triazol-5-yl]-3-phenylpropanoic acid (CAS 1353500-73-8)
- 4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid (CAS 181148-00-5)
- 3-(Tetrahydro-2H-pyran-4-yl)-2-azaspiro[3.3]Heptan-1-one (CAS 1864319-13-0)
- 3,4-Dimethyl-N,N-diphenylaniline (CAS 173460-10-1)
- (R)-1-(3-bromo-4-fluorophenyl)propan-1-amine (CAS 1241682-35-8)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
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