Methyl 3-chloro-5-fluorobenzoate CAS 327056-75-7
| CAS No. | 327056-75-7 |
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 3-chloro-5-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 3-chloro-5-fluorobenzoate (CAS 327056-75-7), molecular formula C8H6ClFO2 and molecular weight 188.58 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Methyl 3-chloro-5-fluorobenzoate (C8H6ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 188.58 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Methyl Standards
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- 2-Chloro-5-fluoro-4-methylbenzoic acid (CAS 103877-61-8)
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Recommended Standards
- Methyl 3-Chloro-4-fluorobenzoate (CAS 234082-35-0)
- Methyl 4-Chloro-3-fluorobenzoate (CAS 206362-87-0)
- Methyl 3-chloro-2-fluorobenzoate (CAS 773874-05-8)
- Methyl 5-chloro-2-fluorobenzoate (CAS 57381-36-9)
- 2-(Ethylsulfanyl)-5-methylaniline (CAS 65523-85-5)
- [(3Z)-1-[(4-Chlorophenyl)methyl]-5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (CAS 303998-48-3)
- n-(2-Aminoethyl)-N-(propan-2-yl)cyclopropanamine (CAS 151793-25-8)
- Ethyl 2-isopropoxy-4-methyl-6-phenylpyrimidine-5-carboxylate (CAS 1245716-70-4)
- Dimethyl 2-(4-hydroxyphenyl)malonate (CAS 80887-78-1)
- 5H-Cyclopenta[c]pyridine-5,7(6H)-dione (CAS 5807-19-2)
- Potassium 4-hydroxy-3-methoxyphenyltrifluoroborate (CAS 1883442-55-4)
- 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (CAS 99087-42-0)
- Acetyl Cedrene (CAS 32388-55-9)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
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