Acetazolamide EP Impurity G CAS 2349-67-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2349-67-9
Molecular FormulaC2H3N3S2
Molecular Weight133.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Acetazolamide EP Impurity G CAS 2349-67-9 chemical structure

Description

Owing to a nitrile group, sulfur-containing functionality, Acetazolamide EP Impurity G is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 133.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Acetazolamide EP Impurity G (CAS 2349-67-9) is a certified pharmaceutical impurity reference standard with the molecular formula C2H3N3S2 and a molecular weight of 133.20 g/mol.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC2H3N3S2
Molecular Weight133.20 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Nitrogen Atoms3
Sulfur Atoms2

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