Thalidomide-O-PEG2-C2-Cl CAS 2349355-96-8
| CAS No. | 2349355-96-8 |
| Molecular Formula | C19H21ClN2O7 |
| Molecular Weight | 424.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Thalidomide-O-PEG2-C2-Cl.
Thalidomide-O-PEG2-C2-Cl (CAS 2349355-96-8), molecular formula C19H21ClN2O7 and molecular weight 424.83 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Thalidomide-O-PEG2-C2-Cl (C19H21ClN2O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 424.83 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21ClN2O7 |
| Molecular Weight | 424.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Thalidomide Standards
- Thalidomide-O-amido-C4-N3 (CAS 2098488-36-7)
- Thalidomide-O-amido-C6-NH2 (CAS 1950635-13-8)
- Thalidomide-O-amido-PEG-C2-NH2 (CAS 2022182-59-6)
- Thalidomide-5'-O-PEG2-C2-azide (CAS 2640388-57-2)
- Thalidomide-O-amido-C3-COOH (CAS 2308035-51-8)
- Thalidomide-C2-amido-C2-COOH (CAS 2353496-84-9)
- Thalidomide-C5-Br (CAS 2411022-24-5)
- Thalidomide-O-PEG3-propargyl (CAS 2098799-76-7)
Recommended Standards
- 3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(4-fluorobenzoyl)-1H-pyrazole (CAS 477711-66-3)
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- Fenquinotrione (CAS 1342891-70-6)
- Cypermethrin Impurity 6 (Mixture of Diastereomers) (CAS 71698-60-7)
- Gadolinium hydroxide hydrate, 99.99% (CAS 100634-91-1)
- Rebaudioside G (CAS 127345-21-5)
- 5-Hydroxy-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-4H-pyran-4-one (CAS 103893-45-4)
- 2-(2-hydroxyethyl)cyclobutanone (CAS 97452-31-8)
- N,N'-bis(4-methylpyridin-2-yl)methanediamine (CAS 344303-26-0)
- rel-(1S,5S,7S)-2-Boc-7-amino-2-azabicyclo[3.2.0]heptane tosylate (CAS 2305079-58-5)
- Lifitegrast Impurity 35 (CAS 2295862-29-0)
- 6-((1,1-Dioxidotetrahydrothiophen-3-yl)carbamoyl)cyclohex-3-ene-1-carboxylic acid (CAS 1218687-78-5)
- 1-(3-{[(2-Amino-ethyl)-isopropyl-amino]-methyl}-piperidin-1-yl)-ethanone (CAS 1354017-52-9)
- Peptide Impurity 34 (CAS 21282-09-7)
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