7-Bromo-5-nitroquinolin-8-ol CAS 23521-17-7
| CAS No. | 23521-17-7 |
| Molecular Formula | C9H5BrN2O3 |
| Molecular Weight | 269.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Bromo-5-nitroquinolin-8-ol.
7-Bromo-5-nitroquinolin-8-ol (CAS 23521-17-7), molecular formula C9H5BrN2O3 and molecular weight 269.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Bromo-5-nitroquinolin-8-ol (C9H5BrN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Bromo-5-nitroquinolin-8-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrN2O3 |
| Molecular Weight | 269.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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- 3-Bromo-1-(4-nitrophenyl)-1H-1,2,4-triazole (CAS 1129540-71-1)
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Recommended Standards
- 7-Bromo-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid (CAS 953754-98-8)
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- 7-Bromo-4-oxo-3,4-dihydrophthalazine-1-carboxylic acid (CAS 2629316-01-2)
- 8-Bromo-3-formylimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 2044836-80-6)
- 4-Methyl-4-(1-pyrrolidinyl)piperidine (CAS 1061683-29-1)
- 1-(2-Hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone (CAS 1246560-24-6)
- 1-tert-Butyl-3,3-Dinitroazetidine (CAS 125735-38-8)
- Ethyl 5-methyl-1-phenyl-1H-pyrazole-4-carboxylate (CAS 89193-16-8)
- 7-isopropyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one (CAS 2489784-39-4)
- Olanzapine Impurity 40 (CAS 1493-27-2)
- Quinuclidine-2-carboxylic acid hydrochloride (CAS 52601-23-7)
- Methyl 1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarboxylate (CAS 1004294-83-0)
- 2,2,2-Trifluoro-N-(2-hydroxycyclopentyl)acetamide (CAS 1864724-99-1)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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