Butylphthalide Impurity 12 CAS 2360-45-4
| CAS No. | 2360-45-4 |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Butylphthalide Impurity 12 (CAS 2360-45-4, C10H10O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H10O3, Butylphthalide Impurity 12 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 178.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Butylphthalide Standards
- Butylphthalide Impurity 54 (CAS 72424-08-9)
- Butylphthalide Impurity N3 (CAS 64002-57-9)
- Butylphthalide Impurity C165 (CAS 4767-54-8)
- Butylphthalide Impurity 19 (CAS 17369-59-4)
- Butylphthalide Impurity 26 (CAS 20871-40-3)
- Butylphthalide Impurity 8 (CAS 1505458-11-6)
- Butylphthalide Impurity N7 (CAS 76681-73-7)
- Butylphthalide Impurity 2 (CAS 551-08-6)
Recommended Standards
- Ipratropium Impurity 11 (CAS 5894-79-1)
- Esmolol Impurity 16 (CAS 19367-38-5)
- Bisoprolol Impurity 36 (CAS 14697-49-5)
- Ozagrel Impurity 17 (CAS 1332370-00-9)
- Bedaquiline Impurity 51 (CAS CATO-C4X-116751)
- Edoxaban Impurity 11 (CAS 41374-72-5)
- Palbociclib Impurity 97 (CAS 775288-71-6)
- 2-(4-(Aminomethyl)-6-(difluoromethyl)-3-methoxypyridin-2-yl)acetic acid (CAS 1361765-48-1)
- trans-4-[2-(4-Iodophenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 736136-61-1)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N,N-diphenylacetamide (CAS 336180-10-0)
- DA8XV9CT34 312696-30-3 Sodium phosphotungstate monohydrate UNII-DA8XV9CT34 Tungstate(3-), tetracosa-mu-oxododecaoxo(mu12-(phosphato(3-)-kappaO:kappaO:kappaO:kappaO':kappaO':kappaO':kappaO'':kappaO'':kappaO'':kappaO''':kappaO''':kappaO'''))dodeca-, trisodium, monohydrate (CAS 312696-30-3)
- Methyl 5-cyclohexyl-1H-pyrrole-2-carboxylate (CAS 1006726-33-5)
- 3-(2-Chloro-7-methylquinolin-3-yl)-5-phenyl-1,2,4-oxadiazole (CAS 1142201-73-7)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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