2-(4-Amino-2-bromophenyl)-2-methylmalononitrile CAS 2360489-96-7
| CAS No. | 2360489-96-7 |
| Molecular Formula | C10H8BrN3 |
| Molecular Weight | 250.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 250.09 g/mol gives 2-(4-Amino-2-bromophenyl)-2-methylmalononitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(4-Amino-2-bromophenyl)-2-methylmalononitrile (CAS 2360489-96-7), a certified reference material (molecular formula C10H8BrN3, MW 250.09 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Amino-2-bromophenyl)-2-methylmalononitrile (C10H8BrN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrN3 |
| Molecular Weight | 250.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-(2-(3-Amino-4-bromo-1h-pyrazol-1-yl)ethoxy)ethan-1-ol (CAS 1250488-95-9)
- 2-Amino-4-(4-bromophenyl)pyrimidine (CAS 392326-81-7)
- 5-Amino-2-(4-bromophenyl)pyrimidine (CAS 84610-01-5)
- Methyl 4-amino-3,5-dichloro-2-methoxybenzoate (CAS 111049-75-3)
- (S)-2-Amino-3-(2,3-dichloro-4-hydroxyphenyl)propanoic acid (CAS 1217611-72-7)
- [2-Amino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]methanol (CAS 1283069-06-6)
- 2-amino-3-(3,5-dichloro-4-hydroxyphenyl)propanoic acid (CAS 15106-62-4)
- Methyl 2-amino-3,5-dichloro-4-methoxybenzoate (CAS 181434-34-4)
Recommended Standards
- 2-(3-Bromophenoxy)pyridine (CAS 92545-83-0)
- 2-(4-Bromophenoxy)pyridine (CAS 4783-82-8)
- 2-(2-Bromophenoxy)pyridine (CAS 94191-74-9)
- 1,2,3,4,5-Pentafluoro-6-(2,2,2-trifluoroethyl)benzene (CAS 27059-24-1)
- 2-Imino-N,1,6-trimethyl-N-phenyl-1,2-dihydropyrimidin-4-amine (CAS 792874-36-3)
- 2-Morpholinopyridin-3-amine dihydrochloride (CAS 1209994-09-1)
- 2-Cyclopropyl-6-(piperidin-1-ylmethyl)pyrimidin-4-ol (CAS 866155-59-1)
- 1-(4-(Trifluoromethyl)pyridin-2-yl)ethanone (CAS 145947-94-0)
- 2-tert-Butyl-2h-1,2,3,4-tetrazol-5-amine (CAS 59772-94-0)
- (1-(Pyrazin-2-yl)piperidin-2-yl)methanol (CAS 1248810-04-9)
- 2-(2,3-Dihydro-1H-indol-1-ylmethyl)-4-fluorophenylamine (CAS 1154634-45-3)
- 2-Ethylthioanisole (CAS 20760-06-9)
- 7'-Chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-[2,6]naphthyridin]-1'-one (CAS 2851437-76-6)
- Liraglutide Impurity 6 TFA Salt (CAS CATO-C4X-19926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com