Tenofovir disoproxil Impurity 105 CAS 2361988-22-7
| CAS No. | 2361988-22-7 |
| Molecular Formula | C9H14N5O4P |
| Molecular Weight | 287.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tenofovir disoproxil Impurity 105 (C9H14N5O4P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 287.21 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tenofovir disoproxil Impurity 105 (CAS 2361988-22-7) is a certified pharmaceutical impurity reference standard with the molecular formula C9H14N5O4P and a molecular weight of 287.21 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tenofovir disoproxil Impurity 105 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H14N5O4P |
| Molecular Weight | 287.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- rac-Tenofovir (CAS 2667563-23-5)
- Tenofovir disoproxil Impurity 120 (CAS 1878175-75-7)
- Tenofovir (CAS 147127-20-6)
- Tenofovir Disoproxil Impurity 26 (CAS 147127-19-3)
- Tenofovir Disoproxil Impurity 30 (CAS CATO-C4X-107630)
- Tenofovir Impurity 68 (CAS 1643116-24-8)
- Tenofovir-d (CAS 1217720-14-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
Recommended Standards
- 4-(2,4-Dichlorophenyl)-n-propyl-1,3-thiazol-2-amine (CAS 556009-97-3)
- 4-Bromo-1-(2-ethylhexyl)-2-fluorobenzene (CAS 1840869-81-9)
- Ethyl 6-fluoro-2-(trifluoromethyl)quinoline-4-carboxylate (CAS 1185292-80-1)
- 1-(3,5-Dichlorophenyl)-4,4-dimethyl-1,4-dihydropyrimidine-2-thiol (CAS 1142212-36-9)
- Octopamine Impurity N1 (CAS 93019-46-6)
- Cefprozil Impurity 42 (CAS CATO-C4X-149242)
- Lacosamide Impurity 55 (CAS CATO-C4X-183055)
- 7OO57LYZ5I 51724-48-2 Trichothecene Trichothec-9-ene UNII-7OO57LYZ5I (CAS 51724-48-2)
- Fumaric acid (disodium) (CAS 17013-01-3)
- N-propyl-m-toluidine (CAS 142031-46-7)
- 5-Cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)-1H-imidazole-2-carboxamide (CAS 1142363-52-7)
- N-Cyclopropyl-4-(piperazin-1-yl)pyrimidin-2-amine (CAS 1201173-18-3)
- 2-Bromo-1-ethyl-4-(trifluoromethyl)-1H-imidazole (CAS 2446482-33-1)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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