(Z)-2-fluorobut-2-enoic acid CAS 2365-87-9
| CAS No. | 2365-87-9 |
| Molecular Formula | C4H5FO2 |
| Molecular Weight | 104.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-2-fluorobut-2-enoic acid.
CATO supplies (Z)-2-fluorobut-2-enoic acid (CAS 2365-87-9), a certified reference material (molecular formula C4H5FO2, MW 104.08 g/mol) for analytical method development and quality control.
The molecular framework of (Z)-2-fluorobut-2-enoic acid (C4H5FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H5FO2 |
| Molecular Weight | 104.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Z Standards
Recommended Standards
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- S-Methylenedioxypyrovalerone Hydrochloride (CAS 1669434-93-8)
- 2-Bromo-5-(pyridin-3-ylmethoxy)pyrazine (CAS 1877094-05-7)
- Ferulic Acid Impurity 1 (CAS 2931-90-0)
- Methyl 3-(cyclopropylamino)-2-methylpropanoate (CAS 1154152-89-2)
- 1H,4H,5H,6H-cyclopenta[b]pyrrole-2-carboxylic acid (CAS 1041429-45-1)
- 5-((4-Fluorophenyl)amino)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 937605-06-6)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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