Nicorandil Impurity 66 CAS 2365474-05-9
| CAS No. | 2365474-05-9 |
| Molecular Formula | C24H27N7O6 |
| Molecular Weight | 509.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Nicorandil Impurity 66 (CAS 2365474-05-9), a pharmacopoeial impurity reference standard (molecular formula C24H27N7O6, MW 509.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C24H27N7O6, Nicorandil Impurity 66 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 509.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Nicorandil Impurity 66 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H27N7O6 |
| Molecular Weight | 509.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 7 |
Related Nicorandil Standards
- Nicorandil Impurity 33 (CAS CATO-C4X-190733)
- Nicorandil Impurity 35 (CAS CATO-C4X-190735)
- Nicorandil impurity 64 (CAS CATO-C4X-190764)
- Nicorandil Impurity 31 (CAS CATO-C4X-190731)
- Nicorandil Impurity 34 (CAS CATO-C4X-190734)
- Nicorandil Impurity 67 (CAS CATO-C4X-190767)
- Nicorandil Impurity 65 (CAS 2250142-70-0)
- Nicorandil Impurity 32 (CAS CATO-C4X-190732)
Recommended Standards
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- Silodosin Carboxylic Acid Impurity (CAS 1357252-79-9)
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- N-(3,5-Difluorobenzyl)-2-oxo-1-(1-(phenylsulfonyl)-1H-indol-5-yl)pyrrolidine-3-carboxamide (CAS 2575547-28-1)
- Bupropion Impurity 44 (CAS 357628-62-7)
- Safinamide Impurity 47 (CAS 1000370-28-4)
- Apremilast impurity 61 (CAS CATO-C4X-100961)
- 4-(Aminomethyl)-2-methyl-5-(trifluoromethoxy)pyridin-3-ol (CAS 1806186-75-3)
- tert-Butyl 2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate (CAS 127708-09-2)
- (E)-Methyl 2-(2-((6-(4-chloro-2-cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate (CAS 131860-80-5)
- 2-Acetamido-5-methylthiazole (CAS 61996-32-5)
- 2-Chloro-1-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethan-1-one (CAS 177489-01-9)
- 2-[4-(cyclopentyloxy)phenyl]Ethylamine hydrochloride (CAS 1235440-38-6)
- Liraglutide Impurity 10 TFA Salt (CAS CATO-C4X-199210)
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