2-Chloro-5-nitro-6-(trifluoromethyl)pyrimidin-4-amine CAS 23663-18-5
| CAS No. | 23663-18-5 |
| Molecular Formula | C5H2ClF3N4O2 |
| Molecular Weight | 242.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-5-nitro-6-(trifluoromethyl)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-5-nitro-6-(trifluoromethyl)pyrimidin-4-amine (CAS 23663-18-5), molecular formula C5H2ClF3N4O2 and molecular weight 242.54 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C5H2ClF3N4O2, 2-Chloro-5-nitro-6-(trifluoromethyl)pyrimidin-4-amine contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 242.54 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2ClF3N4O2 |
| Molecular Weight | 242.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-nitro-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 111928-62-2)
- 2-Chloro-3-nitro-5-(trifluoromethoxy)pyridine (CAS 1361842-46-7)
- 4-Chloro-3-nitro-6-(trifluoromethyl)pyridin-2(1H)-one (CAS 947144-53-8)
- 6-Chloro-5-nitro-2-(trifluoromethyl)pyrimidin-4-amine (CAS 889954-48-7)
- 6-Chloro-2-fluoro-3-(trifluoromethyl)benzoic acid (CAS 1028306-70-8)
- 3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid (CAS 129931-45-9)
- 3-Chloro-2-fluoro-4-(trifluoromethyl)benzoic acid (CAS 1431329-63-3)
- 6-Chloro-2,2,3,3-tetrafluoro-2,3-dihydro-benzo[1,4]dioxine (CAS 151276-12-9)
Recommended Standards
- N,N-diallyl-2,2,2-trichloroacetamide (CAS 39089-57-1)
- 4-Chloro-2-(pentyloxy)phenylboronic acid (CAS 2096338-13-3)
- 5-Fluoro-2-(trifluoromethoxy)benzoyl chloride (CAS 1092460-84-8)
- 3-Chloro-5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2641339-68-4)
- 5-(tert-Butyl)-2-methoxypyridine (CAS 1244949-03-8)
- [1,1'-Biphenyl]-4-yl(2-(phenylamino)thiazol-5-yl)methanone (CAS 339008-29-6)
- (R)-3-Amino-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 791582-16-6)
- Ethyl (1s,3s)-1-amino-3-ethoxycyclobutane-1-carboxylate (CAS 2306249-75-0)
- Metronidazole Impurity 18 (CAS 113385-77-6)
- 2-Amino-3-methoxypropanamide hydrochloride (CAS 17463-68-2)
- Methyl ((benzyloxy)carbonyl)valinate (CAS 134306-34-6)
- 3-(1-Carbamoyl-5-ethyl-3-methyl-1H-pyrazol-4-yl)propanoic acid (CAS 90208-55-2)
- Ciluprevir (CAS 300832-84-2)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
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