Metronidazole Impurity 18 CAS 113385-77-6
| CAS No. | 113385-77-6 |
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Metronidazole Impurity 18 (CAS 113385-77-6) is a certified pharmaceutical impurity reference standard with the molecular formula C6H9N3O3 and a molecular weight of 171.15 g/mol.
Based on its molecular formula C6H9N3O3, Metronidazole Impurity 18 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 171.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
Related Metronidazole Standards
- Metronidazole Impurity 15 (CAS 110578-73-9)
- Metronidazole EP Impurity E (CAS 705-19-1)
- Metronidazole (CAS 443-48-1)
- Metronidazole Impurity N30 (CAS 56910-52-2)
- Metronidazole-d3 (CAS 83413-09-6)
- Metronidazole-13C2,15N2 (CAS 1173020-03-5)
- Metronidazole-d4 (CAS 1261392-47-5)
- Metronidazole Impurity 27 (CAS 34916-84-2)
Recommended Standards
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