Piperazine Impurity 42 CAS 23672-96-0
| CAS No. | 23672-96-0 |
| Molecular Formula | C9H18N2O2 |
| Molecular Weight | 186.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Piperazine Impurity 42.
Piperazine Impurity 42 (CAS 23672-96-0) is a certified pharmaceutical impurity reference standard with the molecular formula C9H18N2O2 and a molecular weight of 186.25 g/mol.
The molecular framework of Piperazine Impurity 42 (C9H18N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H18N2O2 |
| Molecular Weight | 186.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Piperazine Standards
- butyl piperazine-1-carboxylate (CAS 50606-32-1)
- Piperazine Impurity 17 (CAS CATO-C4X-242717)
- SpS)-piperazine-t-butyl-carboxamide (CAS 166941-47-5)
- Piperazine Impurity 9 (CAS CATO-C4X-24279)
- Piperazine Impurity 23 (CAS 61379-66-6)
- 5,5'-(Piperazine-2,5-diyl)bis(2-hydroxybenzamide)Discontinued (CAS 2517940-02-0)
- Piperazine-3,3,5,5-d4-N-t-BOC (CAS 1126621-87-1)
- Piperazine-2-carbohydrazide (CAS 99839-23-3)
Recommended Standards
- 10-Hydroxydec-2-enoic acid (CAS 765-01-5)
- Peridine Impurity 21 (CAS CATO-C4X-239921)
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- Epalrestat Impurity 54 (CAS 1408072-62-7)
- Norepinephrine Impurity 23 (CAS 14771-02-9)
- Aztreonam impurity 102 (CAS CATO-C4X-1522102)
- Cabergoline Impurity 5 (CAS 81409-91-8)
- 2,7-Bis(piperidin-1-ylsulfonyl)-9H-fluoren-9-one (CAS 210411-42-0)
- 3-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 928847-00-1)
- 3,3'-(Carbonylbis(azanediyl))dibenzimidamide (CAS 3459-96-9)
- 1-(4-Chlorobenzenesulfonyl)-4-{[(4-chlorophenyl)sulfanyl]methyl}piperidin-4-ol (CAS 478041-58-6)
- HLI 373 (CAS 1782531-99-0)
- 2-Ethoxy-4-methylpentan-1-amine (CAS 883538-38-3)
- Semaglutide impurity 261 (CAS CATO-C4X-2226261)
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