6,7-Dimethoxy-2-(methylthio)quinazolin-4-amine CAS 23673-10-1
| CAS No. | 23673-10-1 |
| Molecular Formula | C11H13N3O2S |
| Molecular Weight | 251.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6,7-Dimethoxy-2-(methylthio)quinazolin-4-amine (CAS 23673-10-1), molecular formula C11H13N3O2S and molecular weight 251.30 g/mol, is a CATO reference standard with documented purity and traceability.
6,7-Dimethoxy-2-(methylthio)quinazolin-4-amine (C11H13N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13N3O2S |
| Molecular Weight | 251.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dimethoxy Standards
- 3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)propan-1-ol (CAS 148204-28-8)
- (3,4-Dimethoxy-benzyl)-(tetrahydro-furan-2-yl-methyl)-amine (CAS 346704-26-5)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carbohydrazide (CAS 1008052-15-0)
- 2,5-Dimethoxy-4-(4-morpholinyl)benzaldehyde (CAS 154519-07-0)
- (6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-acetic acid (CAS 318465-71-3)
- 11,13-Dimethoxy-3-methyl-4,8-dioxa-3-azatricyclo[7.4.0.0^{2,6}]trideca-1(13),9,11-triene (CAS 400088-00-8)
- 2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid (CAS 68345-67-5)
- 6,7-Dimethoxy-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 105106-20-5)
Recommended Standards
- 6-(Dimethylamino)naphthalene-2-sulfonic acid (CAS 34322-51-5)
- 6-[(2E)-3-(Dimethylamino)prop-2-enoyl]-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one (CAS 343375-28-0)
- 5-[(Ethanesulfonyl)methyl]-3-phenyl-1,2-oxazole (CAS 338962-45-1)
- 6-Benzyl-5-oxothiomorpholine-3-carboxylic acid (CAS 31560-30-2)
- 6-(Cyclopropylmethoxy)pyridazine-3-carboxylic acid (CAS 1184404-57-6)
- 5-Chloro-2,4,6-trifluoroisophthalonitrile (CAS 1897-50-3)
- Kirenol (CAS 52659-56-0)
- (4-Methyl-3-(methylthio)phenyl)methanol (CAS 1896485-52-1)
- Vonoprazan Fumarate Impurity 83 (CAS 928325-41-1 (free base))
- 3,5-Difluoro-4-methoxyphenylacetic acid (CAS 886498-74-4)
- N-benzyl-2-bromothiazole-4-carboxamide (CAS 1449218-23-8)
- (3S,4R)-3-Fluoro-4-methoxypiperidine (CAS 2140267-29-2)
- Methyl 4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxylate (CAS 532391-91-6)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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