5,7-Bis(trifluoromethyl)quinolin-4(1H)-one CAS 237076-72-1
| CAS No. | 237076-72-1 |
| Molecular Formula | C11H5F6NO |
| Molecular Weight | 281.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5,7-Bis(trifluoromethyl)quinolin-4(1H)-one (CAS 237076-72-1), molecular formula C11H5F6NO and molecular weight 281.15 g/mol, is a CATO reference standard with documented purity and traceability.
5,7-Bis(trifluoromethyl)quinolin-4(1H)-one (C11H5F6NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5,7-Bis(trifluoromethyl)quinolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H5F6NO |
| Molecular Weight | 281.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2024 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 2,4-Bis(trifluoromethyl)quinolin-7-ol (CAS 91915-69-4)
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline (CAS 35877-04-4)
- 2,8-Bis(trifluoromethyl)-4-hydroxyquinoline (CAS 35853-41-9)
- 3-(3,5-Bis(trifluoromethyl)phenyl)-3-oxopropanenitrile (CAS 267880-81-9)
- 5-(2,4-Bis(trifluoromethyl)phenyl)oxazole (CAS 2364585-25-9)
- 5-(3,5-Bis(trifluoromethyl)phenyl)oxazole (CAS 2364584-77-8)
- 5-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazole (CAS 1333154-10-1)
- 5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-amine (CAS 51420-72-5)
Recommended Standards
- 5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole, 97% (CAS 478828-53-4)
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- Minocycline-D6 (CAS CATO-C1028952)
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- 3-(2-Bromothiophen-3-yl)propanoic acid (CAS 1540152-03-1)
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Why CATO?
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