Tert-butyl 5-fluoro-3-oxo-3H-spiro[benzofuran-2,4'-piperidine]-1'-carboxylate CAS 2377357-56-5
| CAS No. | 2377357-56-5 |
| Molecular Formula | C17H20FNO4 |
| Molecular Weight | 321.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Tert-butyl 5-fluoro-3-oxo-3H-spiro[benzofuran-2,4'-piperidine]-1'-carboxylate (CAS 2377357-56-5), molecular formula C17H20FNO4 and molecular weight 321.34 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Tert-butyl 5-fluoro-3-oxo-3H-spiro[benzofuran-2,4'-piperidine]-1'-carboxylate (C17H20FNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 321.34 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H20FNO4 |
| Molecular Weight | 321.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-Cyclopentyl-5-(p-tolyl)-2-(trifluoromethyl)pyrimidin-4-amine (CAS 917895-61-5)
- Pitavastatin Impurity 40 (CAS 121659-86-7)
- N-Cyclopentyl-5-(m-tolyl)-2-(trifluoromethyl)pyrimidin-4-amine (CAS 917895-63-7)
- 5-[(4-Fluorophenyl)methyl]-4-oxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline-7-carbonitrile (CAS 1007929-76-1)
- 8-Methoxy-2,3-dimethylquinazolin-4(3H)-one (CAS 104296-30-2)
- 2-Amino-4-(difluoromethyl)pyrimidine-5-carboxylic acid (CAS 1339130-94-7)
- 2-(2-Ethyl-1H-benzo[d]imidazol-5-yl)acetic acid (CAS 1176754-43-0)
- 5-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline (CAS 20226-11-3)
- (3R,5r)-1,1-difluoro-5-methylspiro[2.3]Hexane-5-carboxylic acid (CAS 1773508-84-1)
- 68870-58-6 8163AE C12H10ClNO3 Methyl 3-(4-chlorophenyl)-5-methylisoxazole-4-carboxylate (CAS 68870-58-6)
- 2-(Difluoromethyl)-6-nitro-4H-chromen-4-one (CAS 380593-37-3)
- Clindamycin Impurity 62 (CAS CATO-C4X-134162)
- 6-Benzyl-3-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 80030-90-6)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
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