(R)-6-fluoro-3H-spiro[benzofuran-2,4'-piperidin]-3-amine CAS 2377357-71-4
| CAS No. | 2377357-71-4 |
| Molecular Formula | C12H15FN2O |
| Molecular Weight | 222.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-6-fluoro-3H-spiro[benzofuran-2,4'-piperidin]-3-amine.
CATO supplies (R)-6-fluoro-3H-spiro[benzofuran-2,4'-piperidin]-3-amine (CAS 2377357-71-4), a certified reference material (molecular formula C12H15FN2O, MW 222.26 g/mol) for analytical method development and quality control.
Structurally, (R)-6-fluoro-3H-spiro[benzofuran-2,4'-piperidin]-3-amine (C12H15FN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 222.26 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15FN2O |
| Molecular Weight | 222.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related R Standards
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- 4-Fluoro-3-(4-methyl-1-piperazinyl)benzaldehyde (CAS 1197193-16-0)
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- 2-fluoro-N-(1-methylcyclopentyl)pyridine-4-carboxamide (CAS 1249421-71-3)
- 2-(3-fluoro-4-methoxyphenyl)cyclohexan-1-one (CAS 1311317-72-2)
- 1-[3-(2-Fluoro-phenyl)-piperazin-1-yl]-ethanone (CAS 1316217-70-5)
- 1-[2-(2-Fluoro-phenyl)-piperazin-1-yl]-ethanone (CAS 1316217-77-2)
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Recommended Standards
- (R)-4-(tert-butyl)-2-(5-fluoropyridin-2-yl)-4,5-dihydrooxazole (CAS 2757083-17-1)
- (R)-6-Fluorospiro[chromane-2,1'-cyclopentan]-4-ol (CAS 939411-25-3)
- (R)-2-Amino-4-(((S)-2-amino-2-carboxyethyl)thio)butanoic acid (CAS 30651-43-5)
- (S)-2-Amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene-4-carboxylic acid (CAS 2749964-03-0)
- 1-(4-Chlorophenyl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (CAS 868255-69-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-(2-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 851274-39-0)
- 2-Cyclohexyl-5-hydrazinyl-1,3,4-thiadiazole (CAS 299167-04-7)
- Indium(III) perchlorate hydrate (CAS 314041-16-2)
- N2-benzyl-N6-ethyl-4-(trifluoromethyl)pyridine-2,6-dicarboxamide (CAS 1210695-02-5)
- 4-(5-Hydroxy-3-(4-nitrophenyl)-1H-pyrazol-1-yl)benzamide (CAS 634199-37-4)
- (3aS,6aS)-3a-(Hydroxymethyl)-6a-methyltetrahydro-1H,3H-thieno[3,4-c]furan-1-one (CAS 2679950-66-2)
- ethyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate (CAS 1207175-71-0)
- 3,6-Dimethyl-1H-indole (CAS 81784-48-7)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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