4-Bromo-2-fluoro-3-nitrophenylboronic acid CAS 2377606-27-2
| CAS No. | 2377606-27-2 |
| Molecular Formula | C6H4BBrFNO4 |
| Molecular Weight | 263.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 263.81 g/mol gives 4-Bromo-2-fluoro-3-nitrophenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Bromo-2-fluoro-3-nitrophenylboronic acid (CAS 2377606-27-2) is a high-purity analytical reference standard with the molecular formula C6H4BBrFNO4 and a molecular weight of 263.81 g/mol.
The molecular framework of 4-Bromo-2-fluoro-3-nitrophenylboronic acid (C6H4BBrFNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Bromo-2-fluoro-3-nitrophenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BBrFNO4 |
| Molecular Weight | 263.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
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- 4-(Butylsulfonyl)benzaldehyde (CAS 777953-32-9)
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