3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethoxy)phenol CAS 2377606-48-7
| CAS No. | 2377606-48-7 |
| Molecular Formula | C13H16BF3O4 |
| Molecular Weight | 304.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethoxy)phenol (CAS 2377606-48-7), a certified reference material (molecular formula C13H16BF3O4, MW 304.07 g/mol) for analytical method development and quality control.
3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethoxy)phenol (C13H16BF3O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethoxy)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16BF3O4 |
| Molecular Weight | 304.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Tetramethyl Standards
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethoxy)phenol (CAS 1350989-48-8)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2,2,2-trifluoroethoxy)pyrimidine (CAS 1351234-12-2)
- 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethoxy)pyridin-2-amine (CAS 1620575-08-7)
- 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethoxy)phenol (CAS 1689502-03-1)
- 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(4,4,4-trifluorobutyl)-1H-pyrazole (CAS 1940180-94-8)
- 4,4,5,5-Tetramethyl-2-(4-((trifluoromethyl)thio)phenyl)-1,3,2-dioxaborolane (CAS 1005206-25-6)
- 4,4,5,5-Tetramethyl-2-(3-((trifluoromethyl)thio)phenyl)-1,3,2-dioxaborolane (CAS 1026796-07-5)
- 4-Oxo-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanoic acid (CAS 956139-17-6)
Recommended Standards
- 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidine (CAS 2813245-32-6)
- 4-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 2839742-55-9)
- (4-Iodophenyl)(trifluoromethyl)sulfane (CAS 372-15-6)
- 5-Bromo-3-(3-(trifluoromethyl)-3H-diazirin-3-yl)-1H-indole (CAS 2231673-42-8)
- methyl 6-[(2-fluorophenyl)methoxy]pyridine-3-carboxylate (CAS 1276014-55-1)
- (S)-tert-butyl 3-(hydroxymethyl)morpholine-4-carboxylate (CAS 714971-28-5)
- n-(4-(Difluoromethoxy)phenyl)furan-2-carboxamide (CAS 851872-72-5)
- 3-Bromo-4-nitropyridine hydrochloride (CAS 1416354-31-8)
- (3S,4S)-3-(Boc-amino)-4-azidotetrahydropyran (CAS 1707290-13-8)
- 2-(4-(Difluoromethyl)-6-iodo-2-(trifluoromethyl)pyridin-3-yl)acetic acid (CAS 1804867-93-3)
- Remifentanil EP Impurity C (CAS 132875-68-4)
- H(-Asn-Pro-Asn-Ala)6-OH (CAS 114332-71-7)
- ethyl 4-(N,N-diethylamino)benzoate (CAS 10287-54-4)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
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