4-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyrimidine CAS 2839742-55-9
| CAS No. | 2839742-55-9 |
| Molecular Formula | C12H16BF3N2O3 |
| Molecular Weight | 304.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyrimidine (C12H16BF3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 2839742-55-9), molecular formula C12H16BF3N2O3 and molecular weight 304.07 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16BF3N2O3 |
| Molecular Weight | 304.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidine (CAS 2813245-32-6)
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- N-(2-methoxy-5-nitrophenyl)-N-(methylsulfonyl)glycine (CAS 718603-61-3)
- 2-(4-Methoxy-3-(4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl)propanoic acid (CAS 1437432-59-1)
- 4-Methoxy-3-(phenylsulfonyl)isobenzofuran-1(3H)-one (CAS 74724-81-5)
- 7-Methoxy-3-(phenylsulfonyl)isobenzofuran-1(3H)-one (CAS 65131-09-1)
- 2-Methoxy-6-(2-naphthalen-1-yl-vinyl)-benzoic acid (CAS 1171924-75-6)
Recommended Standards
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- Methyl 3-(5-Bromo-4-fluoro-2-nitrophenyl)acrylate (CAS 2006281-56-5)
- (4-Iodophenyl)(trifluoromethyl)sulfane (CAS 372-15-6)
- 1-(1-Methylpyrrolidin-2-yl)piperazine (CAS 790193-43-0)
- Tert-butyl 4-(4-cyano-3-fluorophenyl)piperazine-1-carboxylate (CAS 204192-44-9)
- 577-64-0 Asterric acid Benzoic acid, 2-(2-carboxy-3-hydroxy-5-methylphenoxy)-5-hydroxy-3-methoxy-, 1-methyl ester (CAS 577-64-0)
- Linagliptin Impurity 6 (CAS CATO-C4X-11016)
- 3-(3-Aminopyrrolidin-1-yl)-1-(2-methoxyphenyl)pyrazin-2(1H)-one (CAS 1707603-33-5)
- 4-[(Benzenesulfonyl)methyl]-6-[(2,4-dichlorophenyl)sulfanyl]-2-methylpyrimidine (CAS 338960-51-3)
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- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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