Methyl 3-((tert-butoxycarbonyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate CAS 2377606-60-3
| CAS No. | 2377606-60-3 |
| Molecular Formula | C18H27BN2O6 |
| Molecular Weight | 378.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 3-((tert-butoxycarbonyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate (CAS 2377606-60-3) is a high-purity analytical reference standard with the molecular formula C18H27BN2O6 and a molecular weight of 378.23 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Methyl 3-((tert-butoxycarbonyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-((tert-butoxycarbonyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H27BN2O6 |
| Molecular Weight | 378.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Ethyl 2-[2,4-dichloro-5-(3,5-dioxo-1,4-thiazinan-4-yl)phenoxy]acetate (CAS 339015-01-9)
- tert-Butyl (4-nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate (CAS 2377609-03-3)
- 7-{[(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]oxy}-2H-1-benzopyran-2-one CBBE (CAS 1522117-80-1)
- Lesinurad Impurity 8 (CAS 1158970-49-0)
- 1-(2-Nitrophenyl)-3-(piperidin-4-yl)urea hydrochloride (CAS 1233952-98-1)
- Tirofiban Impurity 58 (CAS 622-26-4)
- 3-chloro-N-[1-(N’-hydroxycarbamimidoyl)-1-methylethyl]benzamide (CAS 1286215-09-5)
- Adafosbuvir, >98% (HPLC) (CAS 1613589-09-5)
- 4-Bromo-2-(((3-isopropylphenyl)amino)methyl)phenol (CAS 1232802-94-6)
- triphenylmethyl isothiocyanate (CAS 1726-94-9)
- 2-(Dimethylamino)-5-fluorobenzaldehyde (CAS 1096880-71-5)
- N-(5-Ethyl-4-methyl-1H-pyrazol-3-yl)formamide (CAS 75077-06-4)
- 1-Phenyl-1H-[1,2,4]triazole-3-carboxylic acid methylester (CAS 57226-96-7)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
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